BDBM50352761 CHEMBL1823361::US9126931, 353

SMILES CC1(C)c2[nH]c3cc(ccc3c2C(=O)c2cc(CCC3CCCC3)c(cc12)N1CCN(CC1)C1COC1)C#N

InChI Key InChIKey=WDSNMJGRLXTGIN-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50352761   

TargetALK tyrosine kinase receptor(Human)
Chugai Seiyaku Kabushiki Kaisha

US Patent
LigandPNGBDBM50352761(CHEMBL1823361 | US9126931, 353)
Affinity DataIC50: 20.3nMAssay Description:ALK-inhibiting activity was measured by following an activity of inhibiting phosphorylation by biotinylated peptide (EGPWLEEEEEAYGWMDF). For the dete...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2016
Entry Details
Go to US Patent

TargetALK tyrosine kinase receptor(Human)
Chugai Seiyaku Kabushiki Kaisha

US Patent
LigandPNGBDBM50352761(CHEMBL1823361 | US9126931, 353)
Affinity DataIC50: 186nMAssay Description:Inhibition of ALK activity by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50352761(CHEMBL1823361 | US9126931, 353)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of MET activity by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50352761(CHEMBL1823361 | US9126931, 353)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of KIT activity by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50352761(CHEMBL1823361 | US9126931, 353)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of KDR activity by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed