BDBM50353231 CHEMBL1830422

SMILES CCCCCCc1nc2cc(\C=C\C(=O)NO)ccc2n1CCNC(C)C

InChI Key InChIKey=IFKSLVQLRLKBBZ-UHFFFAOYSA-N

Data  11 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50353231   

TargetHistone deacetylase 1(Human)
S*Bio

Curated by ChEMBL
LigandPNGBDBM50353231(CHEMBL1830422)
Affinity DataIC50: 36nMAssay Description:Inhibition of full length recombinant HDAC1 using Fluor de Lys as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetHistone deacetylase 5(Human)
S*Bio

Curated by ChEMBL
LigandPNGBDBM50353231(CHEMBL1830422)
Affinity DataKi:  6.60nMAssay Description:Competitive inhibition of HDAC5 using KI-104 as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetHistone deacetylase 4(Human)
S*Bio

Curated by ChEMBL
LigandPNGBDBM50353231(CHEMBL1830422)
Affinity DataKi:  6.60nMAssay Description:Competitive inhibition of HDAC4 using KI-104 as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetHistone deacetylase 11(Human)
S*Bio

Curated by ChEMBL
LigandPNGBDBM50353231(CHEMBL1830422)
Affinity DataKi:  14nMAssay Description:Competitive inhibition of HDAC11 using KI-104 as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetHistone deacetylase 3(Human)
S*Bio

Curated by ChEMBL
LigandPNGBDBM50353231(CHEMBL1830422)
Affinity DataKi:  15nMAssay Description:Competitive inhibition of HDAC3 using KI-104 as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetHistone deacetylase 9(Human)
S*Bio

Curated by ChEMBL
LigandPNGBDBM50353231(CHEMBL1830422)
Affinity DataKi:  16nMAssay Description:Competitive inhibition of HDAC9 using KI-104 as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
S*Bio

Curated by ChEMBL
LigandPNGBDBM50353231(CHEMBL1830422)
Affinity DataKi:  18nMAssay Description:Competitive inhibition of HDAC2 using KI-104 as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
S*Bio

Curated by ChEMBL
LigandPNGBDBM50353231(CHEMBL1830422)
Affinity DataKi:  20nMAssay Description:Competitive inhibition of HDAC1 using KI-104 as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetPolyamine deacetylase HDAC10(Human)
S*Bio

Curated by ChEMBL
LigandPNGBDBM50353231(CHEMBL1830422)
Affinity DataKi:  29nMAssay Description:Competitive inhibition of HDAC10 using KI-104 as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetHistone deacetylase 7(Human)
S*Bio

Curated by ChEMBL
LigandPNGBDBM50353231(CHEMBL1830422)
Affinity DataKi:  41nMAssay Description:Competitive inhibition of HDAC7 using KI-104 as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
S*Bio

Curated by ChEMBL
LigandPNGBDBM50353231(CHEMBL1830422)
Affinity DataKi:  57nMAssay Description:Competitive inhibition of HDAC8 using KI-104 as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
S*Bio

Curated by ChEMBL
LigandPNGBDBM50353231(CHEMBL1830422)
Affinity DataKi:  348nMAssay Description:Competitive inhibition of HDAC6 using KI-104 as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed