BDBM50353638 CHEMBL1829805

SMILES Clc1ccc(cc1)S(=O)(=O)NCCc1cccc(CC2CC(=O)CC2=O)c1

InChI Key InChIKey=HOVQMBSPXMVMFY-UHFFFAOYSA-N

Data  2 IC50  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50353638   

TargetThromboxane A2 receptor(Human)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50353638(CHEMBL1829805)
Affinity DataKd:  203nMAssay Description:Displacement of [3H]SQ-29548 from human prostanoid TP receptor expressed in QBI-HEK 293A cells after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetThromboxane A2 receptor(Mouse)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50353638(CHEMBL1829805)
Affinity DataKd:  11nMAssay Description:Displacement of [3H]SQ-29548 from mouse prostanoid TP receptor expressed in QBI-HEK 293A cells after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetThromboxane A2 receptor(Human)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50353638(CHEMBL1829805)
Affinity DataIC50: 250nMAssay Description:Antagonist activity at human prostanoid TP receptor expressed in QBI-HEK 293A cells assessed as inhibition of 1-BOP-induced increase in inositol mono...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetThromboxane A2 receptor(Mouse)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50353638(CHEMBL1829805)
Affinity DataIC50: 52nMAssay Description:Antagonist activity at mouse prostanoid TP receptor expressed in QBI-HEK 293A cells assessed as inhibition of 1-BOP-induced increase in inositol mono...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed