BDBM50353647 CHEMBL1829832

SMILES OC(=O)CC(Cc1nc2cc(Cl)cc(Cl)c2[nH]1)c1ccc(Cl)cc1

InChI Key InChIKey=WMLLAHSMFYNLLO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50353647   

TargetProtein kinase C zeta type(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50353647(CHEMBL1829832)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of PKCzeta in human U937 cells assessed as inhibition of TNF-alpha-induced NF-kB activation by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetProtein kinase C zeta type(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50353647(CHEMBL1829832)
Affinity DataIC50: 3.80E+4nMAssay Description:Inhibition of human PKCzeta assessed as [gamma32P]ATP utilization using myelin basic protein as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed