BDBM50353650 CHEMBL1829837

SMILES OC(=O)CC(Cc1nc2ccc(Cl)cc2[nH]1)c1ccc(Cl)c(c1)C(F)(F)F

InChI Key InChIKey=XEVXPFPNNOYXPR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50353650   

TargetProtein kinase C zeta type(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50353650(CHEMBL1829837)
Affinity DataIC50: 2.80E+4nMAssay Description:Inhibition of PKCzeta in human U937 cells assessed as inhibition of TNF-alpha-induced NF-kB activation by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetProtein kinase C zeta type(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50353650(CHEMBL1829837)
Affinity DataIC50: 4.30E+4nMAssay Description:Inhibition of human PKCzeta assessed as [gamma32P]ATP utilization using myelin basic protein as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed