BDBM50353655 CHEMBL1829834

SMILES OC(=O)CC(Cc1nc2ccc(Cl)cc2[nH]1)c1ccc(Cl)c(Cl)c1

InChI Key InChIKey=CWATUWDPAQVYMV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50353655   

TargetProtein kinase C zeta type(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50353655(CHEMBL1829834)
Affinity DataIC50: 3.20E+4nMAssay Description:Inhibition of PKCzeta in human U937 cells assessed as inhibition of TNF-alpha-induced NF-kB activation by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetProtein kinase C zeta type(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50353655(CHEMBL1829834)
Affinity DataIC50: 3.90E+4nMAssay Description:Inhibition of human PKCzeta assessed as [gamma32P]ATP utilization using myelin basic protein as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed