BDBM50353671 CHEMBL1830476

SMILES COc1ccc(nn1)-n1nc(CCC(=O)N2CCN(Cc3ccc(cc3)C(C)(C)C)CC2)cc1-c1ccc(cc1)C(F)(F)F

InChI Key InChIKey=CTSWBBGQRXLCOG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50353671   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Gazi University

Curated by ChEMBL
LigandPNGBDBM50353671(CHEMBL1830476)
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of 5-Lipoxygenase in arachidonic acid-stimulated human neutrophils after 15 mins by HPLC analysis in presence of A23187More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed