BDBM50353838 CHEMBL1830143

SMILES Oc1ccc(\C=C\C(=O)Nc2cccc(Cl)c2)cc1

InChI Key InChIKey=KZKTWYPRMCPYNI-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50353838   

TargetAmine oxidase [flavin-containing] B(Human)
North-West University

Curated by ChEMBL
LigandPNGBDBM50353838(CHEMBL1830143)
Affinity DataIC50: 32nMAssay Description:Inhibition of human recombinant MAO-B assessed as oxidation of kynuramine to 4-hydroxyquinoline after 20 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
North-West University

Curated by ChEMBL
LigandPNGBDBM50353838(CHEMBL1830143)
Affinity DataIC50: 4.73E+4nMAssay Description:Inhibition of human recombinant MAO-A assessed as oxidation of kynuramine to 4-hydroxyquinoline after 20 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50353838(CHEMBL1830143)
Affinity DataIC50: 1.73E+3nMAssay Description:Inhibition of human recombinant MMP2 using succinylated gelatin as substrate incubated for 30 mins prior to substrate addition measured after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50353838(CHEMBL1830143)
Affinity DataIC50: 1.82E+3nMAssay Description:Inhibition of human recombinant MMP9 using succinylated gelatin as substrate incubated for 30 mins prior to substrate addition measured after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50353838(CHEMBL1830143)
Affinity DataIC50: 3.57E+3nMAssay Description:Inhibition of human recombinant MMP1 using succinylated gelatin as substrate incubated for 30 mins prior to substrate addition measured after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed