BDBM50353935 CHEMBL1830885

SMILES Fc1ccccc1N1c2ccccc2N(CC[C@@H]2CNCCO2)S1(=O)=O

InChI Key InChIKey=UIKJCHWTULEUKX-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50353935   

LigandPNGBDBM50353935(CHEMBL1830885)
Affinity DataIC50: 5nMAssay Description:Displacement of [3H]nisoxetine from human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
LigandPNGBDBM50353935(CHEMBL1830885)
Affinity DataIC50: 15nMAssay Description:Inhibition of human NET expressed in MDCK-Net6 cells assessed as inhibition of norepinephrine uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50353935(CHEMBL1830885)
Affinity DataIC50: 2.19E+3nMAssay Description:Displacement of [3H]-WIN-35428 from human DAT expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50353935(CHEMBL1830885)
Affinity DataIC50: 6.41E+3nMAssay Description:Inhibition of human SERT expressed in JAR cells assessed as serotonin uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed