BDBM50353937 CHEMBL1830887

SMILES Fc1ccc(cc1)N1c2ccccc2N(CC[C@@H]2CNCCO2)S1(=O)=O

InChI Key InChIKey=KKELNYPZMKZDOL-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50353937   

TargetSodium-dependent dopamine transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50353937(CHEMBL1830887)
Affinity DataIC50: 211nMAssay Description:Displacement of [3H]-WIN-35428 from human DAT expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
LigandPNGBDBM50353937(CHEMBL1830887)
Affinity DataIC50: 283nMAssay Description:Displacement of [3H]nisoxetine from human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
LigandPNGBDBM50353937(CHEMBL1830887)
Affinity DataIC50: 611nMAssay Description:Inhibition of human NET expressed in MDCK-Net6 cells assessed as inhibition of norepinephrine uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed