BDBM50354027 CHEMBL1830523

SMILES CCC(CC)n1ccc2c(Nc3ccc(OC)cc3Cl)nc3ccnn3c12

InChI Key InChIKey=NLJDWTCQXANWIX-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50354027   

TargetCorticotropin-releasing factor receptor 1(Human)
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50354027(CHEMBL1830523)
Affinity DataEC50:  0.700nMAssay Description:Antagonist activity at human CRF1 receptor expressed in CHO-K1 cells assessed as inhibition of CRF-induced cAMP accumulation after 15 mins by cAMP en...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50354027(CHEMBL1830523)
Affinity DataIC50: 3.20nMAssay Description:Displacement of [125I]-CRF from human CRF1 receptor expressed in CHO-K1 cells after 2 hrs by gamma countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed