BDBM50354392 CHEMBL1836358

SMILES Nc1ncnc2c3ccccc3sc12

InChI Key InChIKey=UWAHPYYKKCDGEN-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50354392   

TargetLIM domain kinase 1(Human)
The Walter and Eliza Hall Institute of Medical Research

Curated by ChEMBL
LigandPNGBDBM50354392(CHEMBL1836358)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of LIMK1 using cofilin-2 as substrate after 60 mins by Kinase-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Rat)
University of Rouen Normandy

Curated by ChEMBL
LigandPNGBDBM50354392(CHEMBL1836358)
Affinity DataIC50: 5.10E+3nMAssay Description:Inhibition of rat recombinant GST-tagged DYRK1A expressed in Escherichia coli using KKISGRLSPIMTEQ as substrate and [gamma32P]ATP after 30 mins by sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCyclin-dependent kinase 5 activator 1(Human)
University of Rouen Normandy

Curated by ChEMBL
LigandPNGBDBM50354392(CHEMBL1836358)
Affinity DataIC50: 5.20E+3nMAssay Description:Inhibition of human recombinant GST-tagged CDK5/p25 expressed in Escherichia coli using histone H1 as substrate and [gamma32P]ATP after 30 mins by sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed