BDBM50354445 CHEMBL1836810

SMILES Cc1cn2c(cnc2c(Nc2ccc(C(=O)N3CCOCC3)c(Cl)c2)n1)-c1cn[nH]c1

InChI Key InChIKey=AXMMFQYWZDPEFR-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50354445   

TargetProtein-tyrosine kinase 6(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50354445(CHEMBL1836810)
Affinity DataIC50: 8nMAssay Description:Inhibition of BRK pretreated for 30 mins by microplate readerMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50354445(CHEMBL1836810)
Affinity DataIC50: 43nMAssay Description:Inhibition of AurBMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetProtein-tyrosine kinase 6(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50354445(CHEMBL1836810)
Affinity DataIC50: 254nMAssay Description:Inhibition of phosphorylation of SAM68 in 293 WT-PTK6 cells after 3 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50354445(CHEMBL1836810)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of LCKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed