BDBM50354827 CHEMBL313528

SMILES CSc1nc(N)nc(SCCN2CCOCC2)n1

InChI Key InChIKey=JOTXSERLGANNBC-UHFFFAOYSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50354827   

TargetHeat shock protein HSP 90-alpha(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50354827(CHEMBL313528)
Affinity DataKd:  2.30E+3nMAssay Description:Binding affinity to human HSP90alpha assessed as 2D1H-15N chemical shift perturbation by NMR spectroscopyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50354827(CHEMBL313528)
Affinity DataIC50: 3.30E+4nMAssay Description:Inhibition of human N-terminal GST-tagged HSP90alpha expressed in Escherichia coli after 1 hr using 10 mM of ATP and malachite green by microplate re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed