BDBM50355408 CHEMBL1835141

SMILES Cn1cc(cn1)-c1ccc2c(c1)[nH]c1c(cnc(NC(C3CC3)C3CC3)c21)C(N)=O

InChI Key InChIKey=MFBHTCKAEJJJMP-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50355408   

TargetTyrosine-protein kinase JAK3(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50355408(CHEMBL1835141)
Affinity DataIC50: 280nMAssay Description:Inhibition of JAK3 using biotin-EQEDEPEGDYFEWLE- NH2 as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50355408(CHEMBL1835141)
Affinity DataIC50: 130nMAssay Description:Inhibition of JAK2-mediated STAT5 phosphorylation in human HEL 92.1.7 irf1-bla cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
LigandPNGBDBM50355408(CHEMBL1835141)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of human hERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50355408(CHEMBL1835141)
Affinity DataIC50: 2nMAssay Description:Inhibition of JAK2 using biotin-EQEDEPEGDYFEWLE- NH2 as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed