BDBM50355415 CHEMBL1833986

SMILES NC(=O)c1cnc(NC(C2CC2)C2CC2)c2c3ccc(cc3[nH]c12)-c1cnc(N)nc1

InChI Key InChIKey=HBDARCLZIJMRIA-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50355415   

TargetTyrosine-protein kinase JAK3(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50355415(CHEMBL1833986)
Affinity DataIC50: 220nMAssay Description:Inhibition of JAK3 using biotin-EQEDEPEGDYFEWLE- NH2 as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50355415(CHEMBL1833986)
Affinity DataIC50: 1nMAssay Description:Inhibition of JAK2 using biotin-EQEDEPEGDYFEWLE- NH2 as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50355415(CHEMBL1833986)
Affinity DataIC50: 29nMAssay Description:Inhibition of JAK2-mediated STAT5 phosphorylation in human HEL 92.1.7 irf1-bla cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
LigandPNGBDBM50355415(CHEMBL1833986)
Affinity DataIC50: 8.20E+3nMAssay Description:Inhibition of human hERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed