BDBM50355445 CHEMBL1835039

SMILES C[C@H](Nc1ccc(C(N)=O)c2[nH]c3cc(ccc3c12)-c1cnn(C)c1)C(C)(C)C

InChI Key InChIKey=LUNNEKXNBPTSAG-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50355445   

TargetTyrosine-protein kinase JAK2(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50355445(CHEMBL1835039)
Affinity DataIC50: 5nMAssay Description:Inhibition of JAK2 using biotin-EQEDEPEGDYFEWLE- NH2 as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50355445(CHEMBL1835039)
Affinity DataIC50: 350nMAssay Description:Inhibition of JAK3 using biotin-EQEDEPEGDYFEWLE- NH2 as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50355445(CHEMBL1835039)
Affinity DataIC50: 370nMAssay Description:Inhibition of JAK2-mediated STAT5 phosphorylation in human HEL 92.1.7 irf1-bla cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
LigandPNGBDBM50355445(CHEMBL1835039)
Affinity DataIC50: 2.90E+4nMAssay Description:Inhibition of human hERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed