BDBM50355461 CHEMBL1835558

SMILES ONC(=O)[C@H]1CCCC[C@H]1NC(=O)c1ccc(Cn2c(nc3ccccc23)C(F)(F)F)nc1

InChI Key InChIKey=FZWNXIRLUBTKJY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50355461   

TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
Sun Pharma Advanced Research

Curated by ChEMBL
LigandPNGBDBM50355461(CHEMBL1835558)
Affinity DataIC50: 280nMAssay Description:Inhibition of TACE in human whole blood assessed as reduction of of LPS-induced TNFalpha production pretreated 15 mins before LPS challenge measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed