BDBM50355550 CHEMBL1910608

SMILES NC(=N)N\N=C/c1c(nc2sc(Br)cn12)-c1ccc(cc1)[N+]([O-])=O

InChI Key InChIKey=MICFEMGUNJSEGM-UHFFFAOYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50355550   

TargetRibosomal protein S6 kinase alpha-3(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50355550(CHEMBL1910608)
Affinity DataIC50: 607nMAssay Description:Inhibition of RSK2 using biotinylated substrate preincubated for 15 mins before substrate addition measured after 30 mins by fluorescence microplate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetRibosomal protein S6 kinase alpha-1(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50355550(CHEMBL1910608)
Affinity DataIC50: 1.18E+3nMAssay Description:Inhibition of RSK1 using biotinylated substrate preincubated for 15 mins before substrate addition measured after 30 mins by fluorescence microplate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetRibosomal protein S6 kinase alpha-3(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50355550(CHEMBL1910608)
Affinity DataIC50: 1.23E+3nMAssay Description:Inhibition of RSK2 assessed as inhibition of substrate phosphorylation using fluorescent peptide substrate by microplate reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk2(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50355550(CHEMBL1910608)
Affinity DataIC50: 1.96E+3nMAssay Description:Inhibition of CHK2 using biotinylated substrate preincubated for 15 mins before substrate addition measured after 30 mins by fluorescence microplate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50355550(CHEMBL1910608)
Affinity DataIC50: 1.38E+4nMAssay Description:Inhibition of CHK1 using biotinylated substrate preincubated for 15 mins before substrate addition measured after 30 mins by fluorescence microplate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetAurora kinase A(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50355550(CHEMBL1910608)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of Aurora A using biotinylated substrate preincubated for 15 mins before substrate addition measured after 30 mins by fluorescence micropl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetALK tyrosine kinase receptor(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50355550(CHEMBL1910608)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of ALK using biotinylated substrate preincubated for 15 mins before substrate addition measured after 30 mins by fluorescence microplate a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk2(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50355550(CHEMBL1910608)
Affinity DataIC50: 8.85E+4nMAssay Description:Inhibition of CHK2 assessed as inhibition of substrate phosphorylation using fluorescent peptide substrate by microplate reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50355550(CHEMBL1910608)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of CHK1 assessed as inhibition of substrate phosphorylation using fluorescent peptide substrate by microplate reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed