BDBM50355880 CHEMBL1910024

SMILES C[C@H](NC(=O)c1cccc2CCc3cc(ccc3Oc12)C(F)(F)F)c1ccc(cc1)C(O)=O

InChI Key InChIKey=HJIUSIWRPBXBTB-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50355880   

TargetProstaglandin E2 receptor EP4 subtype(Human)
Rottapharm Madaus

Curated by ChEMBL
LigandPNGBDBM50355880(CHEMBL1910024)
Affinity DataIC50: 42nMAssay Description:Antagonist activity at human EP4 receptor expressed in HEK293 cells assessed as inhibition of PGE2-induced cAMP accumulation by bead-based proximity ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP4 subtype(Human)
Rottapharm Madaus

Curated by ChEMBL
LigandPNGBDBM50355880(CHEMBL1910024)
Affinity DataIC50: 63nMAssay Description:Displacement of [3H]-PGE2 from human EP4 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP2 subtype(Human)
Rottapharm Madaus

Curated by ChEMBL
LigandPNGBDBM50355880(CHEMBL1910024)
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of [3H]-PGE2 from human EP2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed