BDBM50355934 CHEMBL1910404

SMILES CCNC(=O)Nc1c(c2ccccc2s1)C(=O)N3CCC(CC3)[N@]4CCC[C@@]5(C4)CC(OC5=O)(C)C

InChI Key InChIKey=DSUNZEZCXUMUEH-UHFFFAOYSA-N

Data  4 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50355934   

TargetAcetyl-CoA carboxylase 1(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50355934(CHEMBL1910404)
Affinity DataIC50: 32nMAssay Description:Inhibition of human ACC1More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetAcetyl-CoA carboxylase 2(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50355934(CHEMBL1910404)
Affinity DataIC50: 5.40nMAssay Description:Inhibition of human ACC2More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAcetyl-CoA carboxylase 2(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50355934(CHEMBL1910404)
Affinity DataIC50: 5.40nMAssay Description:Inhibition of human ACC2 using acetyl-coA as substrate incubated for 60 mins prior to substrate addition measured after 20 mins by malachite green as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAcetyl-CoA carboxylase 1(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50355934(CHEMBL1910404)
Affinity DataIC50: 32nMAssay Description:Inhibition of human ACC1 using acetyl-coA as substrate incubated for 60 mins prior to substrate addition measured after 20 mins by malachite green as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed