BDBM50355966 CHEMBL1910897

SMILES C1CN(CCN1)c1ccc(cc1)-c1n[nH]c2nc(ccc12)-c1ccncc1

InChI Key InChIKey=ZNLOPNFHYPMDIP-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50355966   

TargetSerine/threonine-protein kinase pim-1(Human)
Novartis Institutes of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50355966(CHEMBL1910897)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of PIM1 using BAD peptide as substrate preincubated for 15 mins measured after 60 to 100 mins by luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase pim-3(Human)
Novartis Institutes of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50355966(CHEMBL1910897)
Affinity DataIC50: 5.80E+3nMAssay Description:Inhibition of PIM3 using BAD peptide as substrate preincubated for 15 mins measured after 60 to 100 mins by luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase pim-2(Human)
Novartis Institutes of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50355966(CHEMBL1910897)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of PIM2 using BAD peptide as substrate preincubated for 15 mins measured after 60 to 100 mins by luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed