BDBM50355976 CHEMBL1910906

SMILES Nc1ccc(-c2c[nH]c3ccc(cc23)-c2cnccn2)c(F)n1

InChI Key InChIKey=ZAZHHFGHOUJWKE-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50355976   

TargetSerine/threonine-protein kinase pim-1(Human)
Novartis Institutes of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50355976(CHEMBL1910906)
Affinity DataIC50: 250nMAssay Description:Inhibition of PIM1 using BAD peptide as substrate preincubated for 15 mins measured after 60 to 100 mins by luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase pim-3(Human)
Novartis Institutes of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50355976(CHEMBL1910906)
Affinity DataIC50: 310nMAssay Description:Inhibition of PIM3 using BAD peptide as substrate preincubated for 15 mins measured after 60 to 100 mins by luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase pim-2(Human)
Novartis Institutes of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50355976(CHEMBL1910906)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of PIM2 using BAD peptide as substrate preincubated for 15 mins measured after 60 to 100 mins by luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed