BDBM50356372 CHEMBL1911422

SMILES CNc1ccc(NC(=O)c2cn(Cc3c(F)cccc3F)c3ccc(=O)[nH]c3c2=O)cc1

InChI Key InChIKey=XAIXRJONTNTVTN-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50356372   

TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Human)
Biocrea

Curated by ChEMBL

LigandBDBM50356372(CHEMBL1911422)Copy SMILESCopy InChI

Affinity DataIC50: 82nMAssay Description:Inhibition of human recombinant PDE7A1 expressed in baculovirus infected insect Sf21 cells after 30 mins by scintillation proximity assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
7/20/2012
Entry Details Article
Copy BDB DOIPubMed
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TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Human)
Biocrea

Curated by ChEMBL

LigandBDBM50356372(CHEMBL1911422)Copy SMILESCopy InChI

Affinity DataIC50: 994nMAssay Description:Inhibition of human recombinant PDE4A4 expressed in baculovirus infected insect Sf21 cells after 30 mins by scintillation proximity assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
7/20/2012
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL