BDBM50356414 CHEMBL1911570

SMILES COc1cc(NC(=O)c2cn(Cc3c(Cl)cccc3Cl)c3ccc(=O)[nH]c3c2=O)cc(OC)c1OC

InChI Key InChIKey=JELWUFXWZSYANR-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50356414   

TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Human)
Biocrea

Curated by ChEMBL

LigandBDBM50356414(CHEMBL1911570)Copy SMILESCopy InChI

Affinity DataIC50: 88nMAssay Description:Inhibition of human recombinant PDE7A1 expressed in baculovirus infected insect Sf21 cells after 30 mins by scintillation proximity assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
7/20/2012
Entry Details Article
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TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Human)
Biocrea

Curated by ChEMBL

LigandBDBM50356414(CHEMBL1911570)Copy SMILESCopy InChI

Affinity DataIC50: 979nMAssay Description:Inhibition of human recombinant PDE4A4 expressed in baculovirus infected insect Sf21 cells after 30 mins by scintillation proximity assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
7/20/2012
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL