BDBM50356510 CHEMBL1911888

SMILES COc1ccc(CNCCCN(C)c2nc(ns2)-n2ccnc2)cc1OC

InChI Key InChIKey=MUGNXLVOYHPYEX-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50356510   

TargetNitric oxide synthase, inducible(Human)
Kalypsys

Curated by ChEMBL
LigandPNGBDBM50356510(CHEMBL1911888)
Affinity DataEC50:  760nMAssay Description:Inhibition of human iNOS expressed in human HEK293 cells assessed as nitrite accumulation after 18 hrs by 2,3-diaminonapthalene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
Kalypsys

Curated by ChEMBL
LigandPNGBDBM50356510(CHEMBL1911888)
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of human nNOS expressed in HEK293 cells assessed as inhibition ionomycin-induced nitric oxide production incubated for 24 hrs measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Human)
Kalypsys

Curated by ChEMBL
LigandPNGBDBM50356510(CHEMBL1911888)
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of human eNOS expressed in HEK293 cells assessed as inhibition A23187-induced nitric oxide production incubated for 24 hrs measured after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed