BDBM50356574 CHEMBL1909986

SMILES Cc1nc2cn(Cc3ccccc3)cc2c(c1CN)-c1ccc(Cl)cc1Cl

InChI Key InChIKey=DFYJCRFQTFRQQL-UHFFFAOYSA-N

Data  3 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50356574   

TargetCytochrome P450 3A4(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50356574(CHEMBL1909986)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of CYP3A4 in presence of the substrate 7-bezyloxy-4-trifluoromethyl coumarinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50356574(CHEMBL1909986)
Affinity DataIC50: 950nMAssay Description:Inhibition of CYP2C19More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50356574(CHEMBL1909986)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of human ERG by flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50356574(CHEMBL1909986)
Affinity DataIC50: 730nMAssay Description:Inhibition of CYP3A4 in presence of the substrate 7-bezyloxy resorufinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50356574(CHEMBL1909986)
Affinity DataKi:  29nMAssay Description:Inhibition of DPP4More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetDipeptidyl peptidase 8(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50356574(CHEMBL1909986)
Affinity DataKi:  4.25E+3nMAssay Description:Inhibition of DPP8More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetDipeptidyl peptidase 9(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50356574(CHEMBL1909986)
Affinity DataKi:  5.86E+3nMAssay Description:Inhibition of DPP9More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed