BDBM50356920 CHEMBL1915761

SMILES [#6]-[#6@H](-[#6]-[#6]\[#6]=[#6](/[#6]-[#8])-[#6]-[#8])-[#6@H]1-[#6]-[#6][C@@]2([#6])[#6]-3=[#6]-[#6]-[#6@H]4C([#6])([#6])[#6](=O)-[#6]-[#6][C@]4([#6])[#6]-3=[#6]-[#6][C@]12[#6]

InChI Key InChIKey=GTBLGWHADKFJHH-UHFFFAOYSA-N

Data  5 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50356920   

TargetTumor necrosis factor(Human)
The Second People'S Hospital of Fujian Provinc

Curated by ChEMBL
LigandPNGBDBM50356920(CHEMBL1915761)
Affinity DataKd:  17nMAssay Description:Binding affinity to TNF-alpha (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2015
Entry Details Article
PubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Pig)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50356920(CHEMBL1915761)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of pig liver microsomes HMG-CoA reductase incubated for 5 mins in using HMG-CoA and NADPH by colorimetric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2016
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM50356920(CHEMBL1915761)
Affinity DataIC50: 2.18E+4nMAssay Description:Inhibition of AChE assessed as hydrolysis of acetylcholine preincubated for 15 mins measured after 15 mins by colorimetric Ellman assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetCholinesterase(Human)
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM50356920(CHEMBL1915761)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of BChE assessed as hydrolysis of butrylcholine preincubated for 15 mins measured after 15 mins by colorimetric Ellman assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50356920(CHEMBL1915761)
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition of topoisomerase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50356920(CHEMBL1915761)
Affinity DataIC50: 1.06E+5nMAssay Description:Inhibition of topoisomerase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed