BDBM50357154 CHEMBL1917468

SMILES C[C@@H]1CCCN1CCc1ccc(cc1)-c1ccc(=O)n(n1)-c1ccc(F)cc1

InChI Key InChIKey=KTXVIHVCQVKSMA-UHFFFAOYSA-N

Data  2 KI  5 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50357154   

TargetHistamine H3 receptor(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50357154(CHEMBL1917468)
Affinity DataEC50:  2.10nMAssay Description:Inverse agonist activity at human H3R expressed in CHO cells assessed as inhibition of R-alpha-methylhistamine-induced [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50357154(CHEMBL1917468)
Affinity DataKi:  13nMAssay Description:Displacement of [3H]NAMH from human H3R expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetHistamine H3 receptor(Rat)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50357154(CHEMBL1917468)
Affinity DataKi:  48nMAssay Description:Displacement of [3H]NAMH from rat H3R expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50357154(CHEMBL1917468)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50357154(CHEMBL1917468)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP2C19More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50357154(CHEMBL1917468)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50357154(CHEMBL1917468)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP1A2More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50357154(CHEMBL1917468)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed