BDBM50357207 CHEMBL1915364::CHEMBL1963307

SMILES OC(COc1ccc(F)cc1C(=O)CCc1ccccc1)CN1CCN(CC1)C(c1ccccc1)c1ccccc1

InChI Key InChIKey=KTGYQSLCEGJTLM-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50357207   

TargetPotassium voltage-gated channel subfamily H member 2(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50357207(CHEMBL1915364 | CHEMBL1963307)
Affinity DataIC50: 4.84E+3nMAssay Description:Inhibition of human cloned ERG channel expressed in chinese hamster CHO cells after 5 mins by patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetSodium channel protein type 5 subunit alpha(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50357207(CHEMBL1915364 | CHEMBL1963307)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human cloned Nav1.5 channel expressed in chinese hamster CHO cells assessed as tonic inhibition after 5 mins by patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetSodium channel protein type 5 subunit alpha(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50357207(CHEMBL1915364 | CHEMBL1963307)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human cloned Nav1.5 channel expressed in chinese hamster CHO cells assessed as phasic inhibition after 5 mins by patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
LigandPNGBDBM50357207(CHEMBL1915364 | CHEMBL1963307)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human kir6.2/SUR2A ion channel coexpressed in human HEK293 cells after 5 mins by patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50357207(CHEMBL1915364 | CHEMBL1963307)
Affinity DataIC50: 4.84E+3nMAssay Description:Inhibition of human ERG by patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetSodium channel protein type 5 subunit alpha(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50357207(CHEMBL1915364 | CHEMBL1963307)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of Nav1.5 assessed as tonic inhibition by patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetSodium channel protein type 5 subunit alpha(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50357207(CHEMBL1915364 | CHEMBL1963307)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of Nav1.5 assessed as phasic inhibition by patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetATP-sensitive inward rectifier potassium channel 11(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50357207(CHEMBL1915364 | CHEMBL1963307)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of Kir6.2 by patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed