BDBM50357604 CHEMBL1915638

SMILES Fc1ccc(Nc2nc3c(cccc3c3cnccc23)-c2nnc[nH]2)c(F)c1

InChI Key InChIKey=GESRYDOMZCMGNO-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50357604   

TargetSerine/threonine-protein kinase pim-2(Human)
Cylene Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50357604(CHEMBL1915638)
Affinity DataIC50: 6nMAssay Description:Inhibition of human recombinant Pim2 using RSRHSSYPAGT as substrate by radiometric assay in the presence of 5 uM [ATP]More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase pim-1(Human)
Cylene Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50357604(CHEMBL1915638)
Affinity DataIC50: 10nMAssay Description:Inhibition of PIM1 using KKRNRTLTV as substrate by millipore assay in the presence of 90 uM [ATP]More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase pim-2(Human)
Cylene Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50357604(CHEMBL1915638)
Affinity DataIC50: 15nMAssay Description:Inhibition of PIM2 by millipore assay in the presence of 15 uM [ATP]More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase pim-1(Human)
Cylene Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50357604(CHEMBL1915638)
Affinity DataIC50: 16nMAssay Description:Inhibition of human recombinant Pim1 using RSRHSSYPAGT as substrate by radiometric assay in the presence of 30 uM [ATP]More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Cylene Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50357604(CHEMBL1915638)
Affinity DataIC50: 95nMAssay Description:Inhibition of FLT3 using EAIYAAPFAKKK as substrate by radiometric assay in the presence of 200 uM [ATP]More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase pim-3(Human)
Cylene Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50357604(CHEMBL1915638)
Affinity DataIC50: 154nMAssay Description:Inhibition of PIM3 using RSRHSSYPAGT as substrate by radiometric assay in the presence of 155 uM [ATP]More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed