BDBM50357702 CHEMBL1915726

SMILES COc1ccc(COc2ccc(cc2)-c2nn(CCF)cc2-c2ccncc2)nc1

InChI Key InChIKey=RTNYSNRMZBOTJO-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50357702   

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Rat)
Janssen-Cilag

Curated by ChEMBL

LigandBDBM50357702(CHEMBL1915726)Copy SMILESCopy InChI

Affinity DataIC50: 3.16nMAssay Description:Inhibition of rat recombinant PDE10A expressed in baculovirus infected insect Sf9 cells using [3H]cAMP as substrate after 60 mins by scintillation co...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
7/21/2012
Entry Details Article
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TargetSodium-dependent dopamine transporter(Human)
Janssen-Cilag

Curated by ChEMBL

LigandBDBM50357702(CHEMBL1915726)Copy SMILESCopy InChI

Affinity DataIC50: 870nMAssay Description:Inhibition of human DATMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
7/21/2012
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL