BDBM50357737 CHEMBL1915996

SMILES CCCO[C@H]1CN[C@H](C1)[C@@H](O)[C@H](Cc1cc(F)cc(F)c1)NC(=O)[C@H](CCc1ccccc1)N1CC[C@H]([C@H](O)CCC)C1=O

InChI Key InChIKey=XXIRTBPDSKEUAH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50357737   

TargetBeta-secretase 1(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50357737(CHEMBL1915996)
Affinity DataIC50: 48nMAssay Description:Inhibition of BACE1 in human HEK293 cells expressing swedish mutant APPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50357737(CHEMBL1915996)
Affinity DataIC50: 4.70nMAssay Description:Inhibition of BACE1 by HPLC methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed