BDBM50357792 CHEMBL1916569

SMILES CC(C)Oc1cc(ccc1C#N)-c1nc(no1)-c1ccc2N(CCc2c1)C(=O)CCC(O)=O

InChI Key InChIKey=KKTMCFIJPBKYLY-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50357792   

TargetSphingosine 1-phosphate receptor 1(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50357792(CHEMBL1916569)
Affinity DataEC50:  1.10nMAssay Description:Agonist activity at human S1P1 receptor expressed in HEK293 cells assessed as inhibition of forskolin-stimulated cAMP production after 1 hr by HTRF a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 1(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50357792(CHEMBL1916569)
Affinity DataEC50:  6.80nMAssay Description:Agonist activity at recombinant human S1P1 receptor expressed in HEK293 cells after 2 hrs by beta-arrestin assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed