BDBM50358041 CHEMBL1917776

SMILES FC(F)(F)c1cc(ccc1Cl)C(=O)Nc1cccc(c1)C1=Nc2cnn(Cc3ccccc3)c2NC(=O)C1

InChI Key InChIKey=QLQOCYLHRICUMN-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50358041   

TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Hanyang University

Curated by ChEMBL

LigandBDBM50358041(CHEMBL1917776)Copy SMILESCopy InChI

Affinity DataIC50: 961nMAssay Description:Inhibition of human CRAF using [gamma-33P]ATP after 40 mins by scintillation countingMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProtUniProtKB/TrEMBL
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
7/21/2012
Entry Details Article
Copy BDB DOIPubMed
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TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Hanyang University

Curated by ChEMBL

LigandBDBM50358041(CHEMBL1917776)Copy SMILESCopy InChI

Affinity DataIC50: 2.15E+3nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
7/21/2012
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL