BDBM50358220 CHEMBL455389

SMILES CC[C@H](CO)Nc1nc(NCc2cccnc2)c2ncn(C(C)C)c2n1

InChI Key InChIKey=ITWHOUBMQIJNKR-UHFFFAOYSA-N

Data  4 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50358220   

TargetCyclin-H/Cyclin-dependent kinase 7(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50358220(CHEMBL455389)
Affinity DataIC50: 180nMAssay Description:Inhibition of CDK7/cyclin HMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 1(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50358220(CHEMBL455389)
Affinity DataIC50: 2.40E+4nMAssay Description:Inhibition of ERK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50358220(CHEMBL455389)
Affinity DataIC50: 7.40E+3nMAssay Description:Inhibition of CDK1/cyclin BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
LigandPNGBDBM50358220(CHEMBL455389)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at N-type Cav2.2 channel expressed in tsA201 cell assessed as calcium current by whole-cell patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta/[Tau protein] kinase(Pig)
Universite Paris-Descartes

Curated by ChEMBL
LigandPNGBDBM50358220(CHEMBL455389)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of pig brain GSK3alpha/betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed