BDBM50358763 CHEMBL1922476

SMILES FC(F)(F)c1cccc(c1)C(=O)Nc1cccc(Nc2cc3C(=O)NC(=O)c3cc2Cl)c1

InChI Key InChIKey=LMWCSKRGOYUZCO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50358763   

TargetSerine/threonine-protein kinase B-raf(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50358763(CHEMBL1922476)
Affinity DataIC50: 10nMAssay Description:Inhibition of human recombinant his6-tagged B-Raf expressed in Sf9 cells assessed as inhibition of MEK1 phosphorylation after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed