BDBM50359724 CHEMBL1927186

SMILES COc1ccc(cc1)-c1ccc(\C=C2\SC(=S)N(CC(O)=O)C2=O)o1

InChI Key InChIKey=RMYNLYNJRHVJNU-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50359724   

TargetCollagenase 3(Human)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50359724(CHEMBL1927186)
Affinity DataIC50: 1.20E+5nMAssay Description:Inhibition of human MMP13 using Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as substrate pre-incubated for 4 hrs before substrate addition measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetMatrix metalloproteinase-14(Human)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50359724(CHEMBL1927186)
Affinity DataIC50: 3.10E+5nMAssay Description:Inhibition of recombinant human MMP14 catalytic domain using Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as substrate pre-incubated for 4 hrs before...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50359724(CHEMBL1927186)
Affinity DataIC50: 3.50E+5nMAssay Description:Inhibition of human MMP2 using Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as substrate pre-incubated for 4 hrs before substrate addition measured e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetStromelysin-1(Human)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50359724(CHEMBL1927186)
Affinity DataIC50: 8.50E+5nMAssay Description:Inhibition of human MMP3 using Mca-Arg-Pro-Lys-Pro-Val-Glu-Nva-Trp-Arg-Lys(Dnp)-NH2 as substrate pre-incubated for 4 hrs before substrate addition me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50359724(CHEMBL1927186)
Affinity DataIC50: 8.60E+5nMAssay Description:Inhibition of human MMP1 using Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as substrate pre-incubated for 4 hrs before substrate addition measured e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed