BDBM50359725 CHEMBL1927187

SMILES COc1ccc(cc1OC)-c1cs\c(=N/c2ccccc2)n1\N=C\c1ccccc1

InChI Key InChIKey=UEOIUIPMEKCWHI-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50359725   

Target72 kDa type IV collagenase(Human)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50359725(CHEMBL1927187)
Affinity DataIC50: 1.20E+5nMAssay Description:Inhibition of human MMP2 using Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as substrate pre-incubated for 4 hrs before substrate addition measured e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetCollagenase 3(Human)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50359725(CHEMBL1927187)
Affinity DataIC50: 1.40E+5nMAssay Description:Inhibition of human MMP13 using Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as substrate pre-incubated for 4 hrs before substrate addition measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetMatrix metalloproteinase-14(Human)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50359725(CHEMBL1927187)
Affinity DataIC50: 1.50E+5nMAssay Description:Inhibition of recombinant human MMP14 catalytic domain using Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as substrate pre-incubated for 4 hrs before...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetStromelysin-1(Human)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50359725(CHEMBL1927187)
Affinity DataIC50: 2.30E+5nMAssay Description:Inhibition of human MMP3 using Mca-Arg-Pro-Lys-Pro-Val-Glu-Nva-Trp-Arg-Lys(Dnp)-NH2 as substrate pre-incubated for 4 hrs before substrate addition me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50359725(CHEMBL1927187)
Affinity DataIC50: 3.60E+5nMAssay Description:Inhibition of human MMP1 using Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as substrate pre-incubated for 4 hrs before substrate addition measured e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed