BDBM50359985 CHEMBL1927772

SMILES Fc1cc(F)cc(CC(=O)N[C@@H](Cc2ccccc2)C(=O)Nc2ccc(cc2)-c2cn3c(n2)sc2ccccc32)c1

InChI Key InChIKey=KPKMTEIKWRVAML-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50359985   

TargetHepatocyte growth factor receptor(Human)
University of The Mediterranean

Curated by ChEMBL
LigandPNGBDBM50359985(CHEMBL1927772)
Affinity DataIC50: 760nMAssay Description:Inhibition of Met-mediated scattering in HGF-stimulated human MDCK cells pre-incubated overnight prior to HGF stimulation for 24 hrs measured after 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
University of The Mediterranean

Curated by ChEMBL
LigandPNGBDBM50359985(CHEMBL1927772)
Affinity DataIC50: 5.65E+3nMAssay Description:Inhibition of Met-mediated tumorigenesis in HGF-stimulated human GTL16 cells assessed as impairment in anchorage-independent growth by soft agar grow...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed