BDBM50359992 CHEMBL1928311

SMILES Oc1ccc2[nH]c(cc2c1)C(=O)c1cc2c(Nc3ccc(F)c(Cl)c3)ncnc2s1

InChI Key InChIKey=ZWJABXBGZUCAAB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50359992   

TargetEpidermal growth factor receptor(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50359992(CHEMBL1928311)
Affinity DataIC50: 24nMAssay Description:Inhibition of EGFR using poly(Glu,Tyr)4:1 as substrate and [gamma33P]ATP after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50359992(CHEMBL1928311)
Affinity DataIC50: 100nMAssay Description:Inhibition of EGFR autophosphorylation in EGF-stimulated human A431 cells after 1 hr by immunoblottingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed