BDBM50360284 CHEMBL1933068::US9150577, 198

SMILES O=C(Nc1cc(no1)C1CC1)c1ccc2cc3C(=O)NCCCn3c2c1

InChI Key InChIKey=UJAUSTYSRUCHNY-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50360284   

TargetRibosomal protein S6 kinase alpha-2(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM50360284(CHEMBL1933068 | US9150577, 198)
Affinity DataIC50: 18nMpH: 7.5Assay Description:Human RSK2 protein, purchased from Invitrogen, is used to measure kinase activity utilizing Kinase Glo Plus (Promega) a homogeneous assay technology,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2016
Entry Details
Go to US Patent

TargetRibosomal protein S6 kinase alpha-3(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50360284(CHEMBL1933068 | US9150577, 198)
Affinity DataIC50: 250nMAssay Description:Inhibition of human RSK2-mediated CREB phosphorylation in HLR-CREB cells by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetRibosomal protein S6 kinase alpha-3(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50360284(CHEMBL1933068 | US9150577, 198)
Affinity DataIC50: 18nMAssay Description:Inhibition of human RSK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed