BDBM50361184 CHEMBL4169802

SMILES ONC(=O)\C=C\c1ccc(NC(=O)C2CCN(CC2)c2ccc(Nc3nccc(n3)-c3ccc(cc3)C(=O)NCC#N)cc2)cc1

InChI Key InChIKey=XZFBYBMWWNANIK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50361184   

TargetTyrosine-protein kinase JAK2(Human)
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50361184(CHEMBL4169802)
Affinity DataIC50: 15nMAssay Description:Inhibition of JAK2 (unknown origin) using FAM-labeled peptide as substrate preincubated for 10 mins followed by substrate addition and measured after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50361184(CHEMBL4169802)
Affinity DataIC50: 5.10E+3nMAssay Description:Inhibition of full length human recombinant HDAC1 expressed in baculovirus expression system using (Ac-Leu-Gly-Lys(Ac)-AMC as substrate preincubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed