BDBM50361221 CHEMBL1934350

SMILES CS(=O)(=O)N1Cc2cccc(c2C1)-c1ccc2cnc(Nc3ccc(cc3)C3CCN(CC(N)=O)CC3)nn12

InChI Key InChIKey=OBKWVNQNMBDGSL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50361221   

TargetTyrosine-protein kinase JAK2(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50361221(CHEMBL1934350)
Affinity DataIC50: 16nMAssay Description:Inhibition of human recombinant JAK2 expressed in baculovirus expression system after 20 mins by time resolved fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetFocal adhesion kinase 1(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50361221(CHEMBL1934350)
Affinity DataIC50: 205nMAssay Description:Inhibition of human recombinant FAK expressed in baculovirus expression system after 30 mins by time resolved fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed