BDBM50361560 CHEMBL1939486

SMILES CNC(=O)c1cccc(F)c1Nc1nc(Nc2ccc3c(NC(=O)[C@@H](CC3(C)C)NC(=O)C(F)(F)F)c2)ncc1Cl

InChI Key InChIKey=GGJPKPHOWZDYAP-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50361560   

TargetHepatocyte growth factor receptor(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50361560(CHEMBL1939486)
Affinity DataIC50: 26nMAssay Description:Inhibition of GST-tagged c-Met expressed in baculovirus system using phospholipase C-gamma as substrate after 30 mins by time-resolved fluorescence a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetInsulin receptor(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50361560(CHEMBL1939486)
Affinity DataIC50: 583nMAssay Description:Inhibition of insulin receptor after 20 mins by time-resolved fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50361560(CHEMBL1939486)
Affinity DataIC50: 12nMAssay Description:Inhibition of c-Met phosphorylation in human GTL16 cells after 2 hrs by immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed