BDBM50361573 CHEMBL1739063

SMILES FC(F)(F)c1cccc(C(=O)N[C@H]([C@@H]2CCCCN2)c2ccccc2)c1Cl

InChI Key InChIKey=MEZRZVWPLXVLSO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50361573   

TargetSodium- and chloride-dependent glycine transporter 1(Human)
Nagasaki University

Curated by ChEMBL
LigandPNGBDBM50361573(CHEMBL1739063)
Affinity DataIC50: 314nMAssay Description:Inhibition of human GlyT1 expressed in CHO cells assessed as inhibition of [3H]glycine uptake preincubated for 1 mins measured after 2 hrs by liquid ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetSodium- and chloride-dependent glycine transporter 1(Human)
Nagasaki University

Curated by ChEMBL
LigandPNGBDBM50361573(CHEMBL1739063)
Affinity DataIC50: 80nMAssay Description:Inhibition of GlyT1 in human JAR cells assessed as inhibition of [3H]glycine uptake preincubated for 1 mins measured after 2 hrs by liquid scintillat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed