BDBM50361886 CHEMBL1938932

SMILES OC(=O)C1CN(Cc2ccc(-c3nc4ccc(cc4s3)C(=O)N3CCSC3)c(F)c2)C1

InChI Key InChIKey=VGPXQQJRBGSBRP-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50361886   

TargetSphingosine 1-phosphate receptor 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50361886(CHEMBL1938932)
Affinity DataEC50:  2.71E+3nMAssay Description:Agonist activity at human S1P1 receptor expressed in U20S cells coexpressing eGFP assessed as receptor internalization after 1 hr by microscopy analy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 3(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50361886(CHEMBL1938932)
Affinity DataEC50:  7.42E+3nMAssay Description:Agonist activity at human S1P3 receptor expressed in CHO cells coexpressing Gq/i5 protein by calcium flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed