BDBM50361896 CHEMBL1938942

SMILES Cn1cc(C(=O)Nc2ccc(-c3ccccc3)c(c2)C(F)(F)F)c(=O)c2cccnc12

InChI Key InChIKey=CGECRUJWSJMTLZ-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50361896   

TargetSphingosine 1-phosphate receptor 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50361896(CHEMBL1938942)
Affinity DataEC50:  190nMAssay Description:Agonist activity at human S1P1 receptor expressed in human U2OS cells co-expressing eGFP assessed as receptor internalization into cytoplasm using Ho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 3(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50361896(CHEMBL1938942)
Affinity DataEC50:  2.50E+3nMAssay Description:Agonist activity at human S1P3 receptor expressed in CHO-K1 cells co-expressing Gq/i5 G-protein assessed as calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50361896(CHEMBL1938942)
Affinity DataEC50:  190nMAssay Description:Agonist activity at S1P1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed