BDBM50362090 CHEMBL1940275

SMILES COc1cc2ncnc(Nc3ccc(CC(=O)Nc4cnn(c4)C(C)C)cc3)c2cc1OC

InChI Key InChIKey=FQGHYVHLTQUXGX-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50362090   

TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50362090(CHEMBL1940275)
Affinity DataIC50: 20nMAssay Description:Inhibition of Flt3More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50362090(CHEMBL1940275)
Affinity DataIC50: 20nMAssay Description:Inhibition of FLT3 phosphorylation by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50362090(CHEMBL1940275)
Affinity DataIC50: 20nMAssay Description:Inhibition of PDGFRbeta phosphorylation by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50362090(CHEMBL1940275)
Affinity DataIC50: 20nMAssay Description:Inhibition of PDGFRbetaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 3(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50362090(CHEMBL1940275)
Affinity DataIC50: 485nMAssay Description:Inhibition of VEGFR3 phosphorylation by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50362090(CHEMBL1940275)
Affinity DataIC50: 485nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
LigandPNGBDBM50362090(CHEMBL1940275)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of CSF-1RMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
LigandPNGBDBM50362090(CHEMBL1940275)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of CSF1R phosphorylation by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed