BDBM50362181 ({7-[2-(1H-1,2,3-benzotriazol-1-yl)-2-({6-bromo-7-[difluoro(phosphono)methyl]naphthalen-2-yl}methyl)-3-oxo-3-phenylpropyl]-3-bromonaphthalen-2-yl}difluoromethyl)phosphonic acid (10h)::CHEMBL1938814

SMILES OP(O)(=O)C(F)(F)c1cc2cc(CC(Cc3ccc4cc(Br)c(cc4c3)C(F)(F)P(O)(O)=O)(C(=O)c3ccccc3)n3nnc4ccccc34)ccc2cc1Br

InChI Key InChIKey=DELVPFVMXYCLMW-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50362181   

TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Zydus Research Centre

LigandPNGBDBM50362181(CHEMBL1938814 | ({7-[2-(1H-1,2,3-benzotriazol-1-yl...)
Affinity DataIC50: 5nMAssay Description:The in vitro enzyme inhibitory activity was evaluated by using the pNPP assay. Para-nitrophenylphosphate (pNPP) and test compounds were added to assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2014
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Zydus Research Centre

LigandPNGBDBM50362181(CHEMBL1938814 | ({7-[2-(1H-1,2,3-benzotriazol-1-yl...)
Affinity DataIC50: 580nMAssay Description:The in vitro enzyme inhibitory activity was evaluated by using the pNPP assay. Para-nitrophenylphosphate (pNPP) and test compounds were added to assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2014
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Zydus Research Centre

LigandPNGBDBM50362181(CHEMBL1938814 | ({7-[2-(1H-1,2,3-benzotriazol-1-yl...)
Affinity DataIC50: 5nMAssay Description:Inhibition of PTP1B assessed as para-nitrophenyl phosphate catalyzed hydrolysis of para-nitrophenol by p-NPP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Zydus Research Centre

LigandPNGBDBM50362181(CHEMBL1938814 | ({7-[2-(1H-1,2,3-benzotriazol-1-yl...)
Affinity DataIC50: 580nMAssay Description:Inhibition of TCPTPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed